Number of the records: 1
Selective forces for the origin of spliceosomes
Title Selective forces for the origin of spliceosomes Author info Matej Vesteg, Zuzana Šándorová, Juraj Krajčovič Author Vesteg Matej 1982- (60%)
Co-authors Šándorová Zuzana (20%)
Krajčovič Juraj (20%)
Source document Journal of Molecular Evolution. Vol. 74, no. 3-4 (2012), pp. 226-231. - New York : Springer, 2012 Keywords biochémia - biochemistry molekulárna biológia - molekulová biológia - molecular biology evolučná biológia - evolutionary biology Language English Country United States of America systematics 577 Annotation It has been proposed that eukaryotic spliceosomes evolved from bacterial group II introns via constructive neutral changes. However, a more likely interpretation is that spliceosomes and group II introns share a common undefined RNA ancestor—a proto-spliceosome. Although, the constructive neutral evolution may have probably played some roles in the development of complexity including the evolution of modern spliceosomes, in fact, the origin, losses and the retention of spliceosomes can be explained straight-forwardly mainly by positive and negative selection: (1) proto-spliceosomes evolved in the RNA world as a mechanism to excise functional RNAs from an RNA genome and to join noncoding information (ancestral to exons) possibly designed to be degraded. (2) The complexity of proto-spliceosomes increased with the invention of protein synthesis in the RNP world and theywere adopted for (a) the addition of translation signal to RNAs via trans-splicing, and for (b) the exon-shuffling such as to join together exons coding separate protein domains, to translate themas a single unit and thus to facilitate the molecular interaction of protein domains needed to be assembled to functional catalytic complexes. (3) Finally, the spliceosomes were adopted for cis-splicing of (mainly) non-coding information (contemporary introns) to yield translatable mRNAs. (4) Spliceosome-negative organisms (i.e., prokaryotes) have been selected in the DNA–protein world to save a lot of energy. (5) Spliceosome-positive organisms (i.e., eukaryotes) have been selected, because they have been completely spliceosome-dependent Public work category ADC No. of Archival Copy 42335 Repercussion category VOSSEBERG, Julian - SNEL, Berend. Domestication of self-splicing introns during eukaryogenesis : the rise of the complex spliceosomal machinery. In Biology direct. ISSN 1745-6150, 2017, vol. 12, no. 30.
MCNAIR, Jytte Brender - DENNIS, Lynnclaire - KAUFFMAN, Louis H. Mereon matrix, the: Everything connected through (k)nothing. In Mereon Matrix, the : everything connected through (K)nothing. [Singapore] : World scientific publishing, 2018. ISBN 978-981323356-0, pp. 1-846.
MILANOWSKI, Rafal - KARNKOWSKA, Anna - ISHIKAWA, Takao - ZAKRYS, Bozena. Distribution of conventional and nonconventional introns in tubulin (alpha and beta) genes of euglenids. In Molecular biology and evolution. ISSN 0737-4038, 2014, vol. 31, no. 3, pp. 584-593.
DENNIS, L. - MCNAIR, J. Brender - REID, J. S. Dedication to Dr. Robert W. "Bob" Gray. In Mereon matrix : everything connected through (k)nothing. ISSN 0219-9769, 2018, vol. 62, pp. V-+.
PENNY, David - COLLINS, Lesley J. - DALY, Toni K. - COX, Simon J. The relative ages of Eukaryotes and Akaryotes. In Journal of molecular evolution. ISSN 0022-2844, 2014, vol. 79, no. 5-6, special issue, pp. 228-239.
IRIMIA, Manuel - ROY, Scott William. Origin of spliceosomal introns and alternative splicing. In Cold spring harbor perspectives in biology. ISSN 1943-0264, 2014, vol. 6, no. 6, pp. 1-24.
ISOMOTO, Nana - MAEDA, Yuri - TANAKA, Takahiro - FURUTA, Hiroyuki - IKAWA, Yoshiya. Fixation and accumulation of thermotolerant catalytic competence of a pair of ligase ribozymes through complex formation and cross ligation. In Journal of molecular evolution. ISSN 0022-2844, 2013, vol. 76, no. 1-2, pp. 48-58.
DENNIS, L. Preface observational evidence, mathematical verification and inimitable grace. In Mereon matrix : unity, perspective and paradox. Amsterdam : Elsevier, 2013. ISBN 978-0-12-404688-7, pp. XIX-+.
STOLTZFUS, Arlin. Constructive neutral evolution : exploring evolutionary theory's curious disconnect. In Biology direct. ISSN 1745-6150, 2012, vol. 7, art. no. 35, pp. 1-13.
MUSTAFIN, R. N. Basic mechanisms of the origin and evolution of protein-coding genes. In Uspekhi fiziologicheskikh nauk. ISSN 0301-1798, 2020, vol. 51, no. 4, pp. 64-81.
Catal.org. BB301 - Univerzitná knižnica Univerzity Mateja Bela v Banskej Bystrici Database xpca - PUBLIKAČNÁ ČINNOSŤ References PERIODIKÁ-Súborný záznam periodika 
unrecognised
Number of the records: 1